DKK1 anticorps (C-Term)

N° du produit ABIN2773909

Détail du produit anti-DKK1 anticorps

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Lapin, Chévre, Cobaye, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est non-conjugé

Application: Western Blotting (WB)

Séquence: CARHFWSKIC KPVLKEGQVC TKHRRKGSHG LEIFQRCYCG EGLSCRIQKD

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DKK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DKK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 266 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: DKK1 (DKK1 Produits)

Synonymes: anticorps DKK-1, anticorps SK, anticorps AI414495, anticorps SGY, anticorps SGY-1, anticorps SGY1, anticorps Soggy, anticorps mSgy, anticorps dkk1, anticorps dkk, anticorps dkk-1, anticorps xdkk1, anticorps Xdkk-1, anticorps Dickkopf1, anticorps dickkopf-1, anticorps mdkk-1, anticorps dkk1-A, anticorps dickkopf WNT signaling pathway inhibitor 1, anticorps dickkopf like acrosomal protein 1, anticorps dickkopf-related protein 1, anticorps dickkopf-like 1, anticorps dickkopf WNT signaling pathway inhibitor 1b, anticorps dickkopf protein, anticorps dickkopf WNT signaling pathway inhibitor 1 S homeolog, anticorps DKK1, anticorps Dkk1, anticorps DKKL1, anticorps LOC100228789, anticorps Dkkl1, anticorps dkk1b, anticorps dkk1, anticorps dickkopf, anticorps dkk1.S

Sujet: DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Alias Symbols: DKK-1, SK
Protein Interaction Partner: KRTAP10-1, LRP6, MDFI, LRP5, DPP4, SMAD9, KREMEN1, CORO1A, CTNNB1,
Protein Size: 266

Poids moléculaire: 26 kDa

ID gène: 22943

NCBI Accession: NM_012242, NP_036374

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation