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C-JUN anticorps (N-Term)

JUN Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2774668
  • Antigène Voir toutes C-JUN (JUN) Anticorps
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Épitope
    • 42
    • 42
    • 30
    • 29
    • 22
    • 16
    • 16
    • 15
    • 11
    • 11
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 380
    • 207
    • 190
    • 34
    • 27
    • 21
    • 18
    • 17
    • 16
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Cobaye
    Hôte
    • 371
    • 17
    • 2
    Lapin
    Clonalité
    • 346
    • 44
    Polyclonal
    Conjugué
    • 190
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 13
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp C-JUN est non-conjugé
    Application
    • 270
    • 136
    • 121
    • 89
    • 57
    • 46
    • 43
    • 43
    • 43
    • 23
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MCTKMEQPFY HDDSYTATGY GRAPGGLSLH DYKLLKPSLA VNLADPYRSL
     Réactivité croisée
    Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against JUNB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human JUNB
    Top Product
    Discover our top product JUN Anticorps primaire
  • Indications d'application
    WB Suggested Anti-JUNB Antibody Titration: 1.25 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: Transfected 293T.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 347 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Autre désignation
    Jun (JUN Produits)
    Synonymes
    anticorps AP-1, anticorps AP1, anticorps c-Jun, anticorps fj36h07, anticorps wu:fj36h07, anticorps zgc:65863, anticorps Junc, anticorps c-jun, anticorps CG2275, anticorps D-Jun, anticorps D-jun, anticorps D-jun/Jra, anticorps DJUN, anticorps DJun, anticorps Djun, anticorps Dmel\\CG2275, anticorps JRA, anticorps JUN, anticorps Jun, anticorps V, anticorps cJun, anticorps d-JRA, anticorps d-Jun, anticorps d-jun, anticorps dAP-1, anticorps dJRA, anticorps dJUN, anticorps dJra, anticorps dJun, anticorps djun, anticorps dm-Jun, anticorps jra, anticorps jun, anticorps l(2)46Ef, anticorps l(2)IA109, anticorps l(2R)IA109, anticorps Jun proto-oncogene, AP-1 transcription factor subunit, anticorps jun proto-oncogene S homeolog, anticorps jun proto-oncogene, anticorps Jun-related antigen, anticorps jun proto-oncogene L homeolog, anticorps JUN, anticorps Jun, anticorps jun.S, anticorps jun, anticorps Jra, anticorps jun.L
    Sujet
    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation.
    Alias Symbols: AP-1
    Protein Interaction Partner: BATF, FOS, RFWD2, C19orf68, USP24, TCERG1, ZNF595, PKIA, MAP2, APLP2, FOSL1, DDIT3, ATF3, BATF2, BATF3, TCL1A, FOSL2, NPM1, NEU1, SMAD4, HOXA7, BDNF, ATF4, MAPK6, UBC, TDG, SET, SAT1, MAPK9, BRCA1, SUMO2, Cebpb, EP300, SMURF1, YY1, CREBBP, SMARCA4, JDP2,
    Protein Size: 347
    Poids moléculaire
    36 kDa
    ID gène
    3726
    NCBI Accession
    NM_002229, NP_002220
    UniProt
    P17275
    Pathways
    Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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