Annexin A3 anticorps (N-Term)

N° du produit ABIN2774839

Détail du produit anti-Annexin A3 anticorps

Antigène: Annexin A3 (ANXA3)

Épitope: N-Term

Reactivité: Humain, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Annexin A3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MASIWVGHRG TVRDYPDFSP SVDAEAIQKA IRGIGTDEKM LISILTERSN

Homologie: Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ANXA3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Annexin A3 (ABIN2774839)

Meyer-Schwesinger, Dehde, Klug, Becker, Mathey, Arefi, Balabanov, Venz, Endlich, Pekna, Gessner, Thaiss, Meyer: "Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 6, pp. 3218-29, (2011) (PubMed).

Bianchi, Bombelli, Raimondo, Torsello, Angeloni, Ferrero, Di Stefano, Chinello, Cifola, Invernizzi, Brambilla, Magni, Pitto, Zanetti, Mocarelli, Perego: "Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3." dans: The American journal of pathology, Vol. 176, Issue 4, pp. 1660-70, (2010) (PubMed).

Schordan, Schordan, Endlich, Lindenmeyer, Meyer-Schwesinger, Meyer, Giebel, Cohen, Endlich, Maurer: "Alterations of the podocyte proteome in response to high glucose concentrations." dans: Proteomics, Vol. 9, Issue 19, pp. 4519-28, (2009) (PubMed).

Seliger, Dressler, Wang, Kellner, Recktenwald, Lottspeich, Marincola, Baumgärtner, Atkins, Lichtenfels: "Combined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma." dans: Proteomics, Vol. 9, Issue 6, pp. 1567-81, (2009) (PubMed).

Détails sur Annexin A3

Antigène: Annexin A3 (ANXA3)

Autre désignation: ANXA3 (ANXA3 Produits)

Synonymes: anticorps MGC80326, anticorps anxa3, anticorps zgc:101718, anticorps ANXA3, anticorps ANX3, anticorps Anx3, anticorps LC3, anticorps LRRGT00047, anticorps annexin A3 L homeolog, anticorps annexin A3a, anticorps annexin A3, anticorps Annexin A3, anticorps anxa3.L, anticorps anxa3a, anticorps ANXA3, anticorps anxa3, anticorps Anxa3

Sujet: The ANXA3 gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Alias Symbols: ANX3
Protein Interaction Partner: UBC, ATF2, SNAP23, STXBP2, STX4, ANXA11, ANXA4, ISG15, EMG1, IGSF21, UBR1, UNC119, TP53, REG3A,
Protein Size: 323

Poids moléculaire: 36 kDa

ID gène: 306

NCBI Accession: NM_005139, NP_005130

UniProt: P12429