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Angiotensin II Type-1 Receptor anticorps (N-Term)

AGTR1 Reactivité: Humain, Rat, Souris, Chien, Lapin, Cobaye, Boeuf (Vache), Mouton, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775286
  • Antigène Voir toutes Angiotensin II Type-1 Receptor (AGTR1) Anticorps
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Épitope
    • 16
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 49
    • 22
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Chien, Lapin, Cobaye, Boeuf (Vache), Mouton, Cheval
    Hôte
    • 47
    • 3
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 51
    • 3
    Polyclonal
    Conjugué
    • 32
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Angiotensin II Type-1 Receptor est non-conjugé
    Application
    • 31
    • 23
    • 17
    • 15
    • 13
    • 10
    • 9
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Séquence
    ILNSSTEDGI KRIQDDCPKA GRHNYIFVMI PTLYSIIFVV GIFGNSLVVI
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against AGTR1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human AGTR1
    Top Product
    Discover our top product AGTR1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 359 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Autre désignation
    AGTR1 (AGTR1 Produits)
    Synonymes
    anticorps AG2S, anticorps AGTR1A, anticorps AGTR1B, anticorps AT1, anticorps AT1AR, anticorps AT1B, anticorps AT1BR, anticorps AT1R, anticorps AT2R1, anticorps AT2R1A, anticorps AT2R1B, anticorps HAT1R, anticorps 1810074K20Rik, anticorps AI551199, anticorps AT1a, anticorps Agtr-1a, anticorps Agtr1, anticorps Angtr-1a, anticorps AT1A, anticorps XAT-1, anticorps agtr1-A, anticorps agtr1.2, anticorps AT1-R, anticorps at1, anticorps AGTR1, anticorps Agtr-1b, anticorps Angtr-1b, anticorps agtr1, anticorps agtr1-a, anticorps agtr1-b, anticorps xAT, anticorps angiotensin II receptor type 1, anticorps angiotensin II receptor, type 1a, anticorps angiotensin II receptor type 1 S homeolog, anticorps uncharacterized AGTR1, anticorps angiotensin II receptor, type 1b, anticorps angiotensin II receptor type 1 L homeolog, anticorps AGTR1, anticorps Agtr1a, anticorps agtr1.S, anticorps Agtr1, anticorps Agtr1b, anticorps agtr1.L
    Sujet
    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. AGTR1 is the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans.Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.
    Alias Symbols: AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1R
    Protein Interaction Partner: PDE6H, GNB2L1, HTR2B, ARRB2, ARRB1, JAK2, TRAF3, MAPK1, AGTRAP, DNAJC14, THOP1, GRK5, GPRASP1, HRAS, RAB5A, PLCG1, RAF1, NOS3, EGFR, BDKRB2, ADRBK2, ADRBK1, AGT, ZBTB16,
    Protein Size: 359
    Poids moléculaire
    41 kDa
    ID gène
    185
    NCBI Accession
    NM_004835, NP_004826
    UniProt
    P30556
    Pathways
    Signalistation JAK/STAT, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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