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CBX1 anticorps (Middle Region)

CBX1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775788
  • Antigène Voir toutes CBX1 Anticorps
    CBX1 (Chromobox Homolog 1 (CBX1))
    Épitope
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 46
    • 19
    • 15
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cheval, Lapin, Cobaye
    Hôte
    • 35
    • 9
    • 1
    • 1
    Lapin
    Clonalité
    • 35
    • 10
    • 1
    Polyclonal
    Conjugué
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CBX1 est non-conjugé
    Application
    • 35
    • 25
    • 9
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human CBX1
    Top Product
    Discover our top product CBX1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 185 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    CBX1 (Chromobox Homolog 1 (CBX1))
    Autre désignation
    CBX1 (CBX1 Produits)
    Synonymes
    anticorps CBX, anticorps HP1-BETA, anticorps HP1Hs-beta, anticorps HP1Hsbeta, anticorps M31, anticorps MOD1, anticorps p25beta, anticorps Cbx, anticorps Cbx-rs2, anticorps E430007M08Rik, anticorps HP1B, anticorps Hp1beta, anticorps cbx1, anticorps wu:fe14b09, anticorps zgc:55739, anticorps zgc:86924, anticorps chromobox 1, anticorps chromobox homolog 1a (HP1 beta homolog Drosophila), anticorps chromobox 1 S homeolog, anticorps chromobox homolog 1b (HP1 beta homolog Drosophila), anticorps CBX1, anticorps Cbx1, anticorps cbx1a, anticorps cbx1.S, anticorps cbx1b
    Sujet
    CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].
    Alias Symbols: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
    Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
    Protein Size: 185
    Poids moléculaire
    21 kDa
    ID gène
    10951
    NCBI Accession
    NM_006807, NP_006798
    UniProt
    P83916
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