WNT2B anticorps (Middle Region)

N° du produit ABIN2776710

Détail du produit anti-WNT2B anticorps

Antigène: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LRTCWRALSD FRRTGDYLRR RYDGAVQVMA TQDGANFTAA RQGYRRATRT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WNT2B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WNT2B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 372 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-WNT2B (ABIN2776710)

Chigita, Sugiura, Abe, Kobayashi, Shimoda, Onoda, Shirasuna: "CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of ?-catenin in carcinoma cells." dans: International journal of oncology, Vol. 41, Issue 6, pp. 2021-8, (2012) (PubMed).

Détails sur WNT2B

Antigène: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Autre désignation: WNT2B (WNT2B Produits)

Synonymes: anticorps WNT13, anticorps XWNT2, anticorps wnt2b, anticorps XWnt-2, anticorps Xwnt-2b, anticorps wnt-2b, anticorps xwnt2b, anticorps WNT2B, anticorps Wnt13, anticorps Wnt family member 2B, anticorps wingless-type MMTV integration site family, member 2Ba, anticorps Wnt family member 2B L homeolog, anticorps wingless-type MMTV integration site family, member 2B, anticorps wingless-type MMTV integration site family, member 2Bb, anticorps WNT2B, anticorps Wnt2b, anticorps wnt2ba, anticorps wnt2b.L, anticorps wnt2bb

Sujet: WNT2B is a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.
Alias Symbols: WNT13, XWNT2
Protein Interaction Partner: RAD21, BRCA1,
Protein Size: 372

Poids moléculaire: 41 kDa

ID gène: 7482

NCBI Accession: NM_004185, NP_004176

UniProt: Q5T6U1

Pathways: Signalisation WNT