CYP1A1 anticorps (Middle Region)

N° du produit ABIN2776793

Détail du produit anti-CYP1A1 anticorps

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Mouton, Chien, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV

Homologie: Cow: 93%, Dog: 83%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CYP1A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CYP1A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 512 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP1A1

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Autre désignation: CYP1A1 (CYP1A1 Produits)

Synonymes: anticorps AHH, anticorps AHRR, anticorps CP11, anticorps CYP1, anticorps P1-450, anticorps P450-C, anticorps P450DX, anticorps Cyp1a2, anticorps P450-1, anticorps cyp1a1, anticorps CYP1A1, anticorps CYPIA1, anticorps Cyp45c, anticorps Cypc45c, anticorps P-450MC, anticorps wu:fb63b04, anticorps zfCYP1A, anticorps zgc:109747, anticorps ahh, anticorps ahrr, anticorps cp11, anticorps cyp1, anticorps cyp1a, anticorps p1-450, anticorps p450-c, anticorps p450dx, anticorps cytochrome P450 family 1 subfamily A member 1, anticorps cytochrome P450 1A1, anticorps cytochrome P450, family 1, subfamily a, polypeptide 1, anticorps cytochrome P450, family 1, subfamily A, polypeptide 1, anticorps cytochrome P450 family 1 subfamily D polypeptide 1, anticorps cytochrome P4501A1, anticorps polycyclic hydrocarbon-inducible cytochrome P450c, anticorps cytochrome P450, family 1, subfamily A, anticorps cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1, anticorps cytochrome P450 family 1 subfamily A member 1 L homeolog, anticorps CYP1A1, anticorps CpipJ_CPIJ010542, anticorps Cyp1a1, anticorps cyp1d1, anticorps LOC100328613, anticorps cyp1a, anticorps LOC102129994, anticorps cyp1a1.L

Sujet: CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Protein Interaction Partner: CMTM5, CYB5A,
Protein Size: 512

Poids moléculaire: 58 kDa

ID gène: 1543

NCBI Accession: NM_000499, NP_000490

UniProt: P04798

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha