Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ASL anticorps (N-Term)

ASL Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin, Chien, Chévre, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776927
  • Antigène Voir toutes ASL Anticorps
    ASL (Argininosuccinate Lyase (ASL))
    Épitope
    • 15
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 49
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Lapin, Chien, Chévre, Saccharomyces cerevisiae
    Hôte
    • 44
    • 5
    Lapin
    Clonalité
    • 46
    • 3
    Polyclonal
    Conjugué
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASL est non-conjugé
    Application
    • 36
    • 13
    • 13
    • 11
    • 11
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    GATAGKLHTG RSRNDQVVTD LRLWMRQTCS TLSGLLWELI RTMVDRAEAE
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ASL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human ASL
    Top Product
    Discover our top product ASL Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 464 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Trevisson, Salviati, Baldoin, Toldo, Casarin, Sacconi, Cesaro, Basso, Burlina: "Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene." dans: Human mutation, Vol. 28, Issue 7, pp. 694-702, (2007) (PubMed).

  • Antigène
    ASL (Argininosuccinate Lyase (ASL))
    Autre désignation
    ASL (ASL Produits)
    Synonymes
    anticorps ASAL, anticorps 2510006M18Rik, anticorps zgc:63532, anticorps BA4879, anticorps PSPTO0125, anticorps Adl, anticorps Asl, anticorps argininosuccinate lyase, anticorps argininosuccinate lyase ArgH, anticorps adenylosuccinate lyase, anticorps argininosuccinate lyase L homeolog, anticorps ASL, anticorps Asl, anticorps asl, anticorps argH2, anticorps argH, anticorps arg7, anticorps CNC04420, anticorps STHERM_c13370, anticorps Adsl, anticorps asl.L, anticorps ARG7
    Sujet
    ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: ASAL
    Protein Interaction Partner: WDYHV1, ASL, GINS4, NCDN, TUFM, PDHA1, NEDD8, HK1, GDI1, BAG3, OVGP1, HMOX1, FBP1, CSNK2A2, UBC, QARS,
    Protein Size: 464
    Poids moléculaire
    52 kDa
    ID gène
    435
    NCBI Accession
    NM_000048, NP_000039
    UniProt
    P04424
    Pathways
    Response to Growth Hormone Stimulus
Vous êtes ici:
Support technique