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PIAS3 anticorps (Middle Region)

PIAS3 Reactivité: Humain, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777575
  • Antigène Voir toutes PIAS3 Anticorps
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    Épitope
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 33
    • 18
    • 16
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin
    Hôte
    • 30
    • 3
    Lapin
    Clonalité
    • 30
    • 2
    Polyclonal
    Conjugué
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIAS3 est non-conjugé
    Application
    • 24
    • 15
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK
    Homologie
    Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human PIAS3
    Top Product
    Discover our top product PIAS3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 628 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    Autre désignation
    PIAS3 (PIAS3 Produits)
    Synonymes
    anticorps PIAS3, anticorps Pias3l, anticorps ZMIZ5, anticorps protein inhibitor of activated STAT 3, anticorps protein inhibitor of activated STAT, 3, anticorps protein inhibitor of activated STAT 3 L homeolog, anticorps PIAS3, anticorps pias3, anticorps Pias3, anticorps pias3.L
    Sujet
    PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ14651, ZMIZ5
    Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
    Protein Size: 628
    Poids moléculaire
    68 kDa
    ID gène
    10401
    NCBI Accession
    NM_006099, NP_006090
    UniProt
    Q9Y6X2
    Pathways
    Signalistation JAK/STAT
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