PIAS3 anticorps (Middle Region)
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- Antigène Voir toutes PIAS3 Anticorps
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Chien, Boeuf (Vache), Cheval, Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PIAS3 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DEIQFMEDGS WCPMKPKKEA SEVCPPPGYG LDGLQYSPVQ GGDPSENKKK
- Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PIAS3
- Top Product
- Discover our top product PIAS3 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 628 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
- Autre désignation
- PIAS3 (PIAS3 Produits)
- Synonymes
- anticorps PIAS3, anticorps Pias3l, anticorps ZMIZ5, anticorps protein inhibitor of activated STAT 3, anticorps protein inhibitor of activated STAT, 3, anticorps protein inhibitor of activated STAT 3 L homeolog, anticorps PIAS3, anticorps pias3, anticorps Pias3, anticorps pias3.L
- Sujet
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PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses. This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ14651, ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 628 - Poids moléculaire
- 68 kDa
- ID gène
- 10401
- NCBI Accession
- NM_006099, NP_006090
- UniProt
- Q9Y6X2
- Pathways
- Signalistation JAK/STAT
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