SNF8 anticorps (N-Term)

N° du produit ABIN2777633

Détail du produit anti-SNF8 anticorps

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Snf8. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 258 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNF8

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Autre désignation: Snf8 (SNF8 Produits)

Synonymes: anticorps d11moh34, anticorps vps22, anticorps Dot3, anticorps EAP30, anticorps VPS22, anticorps D11moh34, anticorps RGD1310144, anticorps D11Moh34, anticorps D11MOH34, anticorps zgc:101578, anticorps SNF8, ESCRT-II complex subunit, anticorps eap30 subunit of ell complex, putative, anticorps EAP30 subunit of ELL complex, anticorps SNF8, ESCRT-II complex subunit S homeolog, anticorps SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), anticorps snf8, anticorps TA17290, anticorps TVAG_107410, anticorps Bm1_05145, anticorps SNF8, anticorps Snf8, anticorps snf8.S

Sujet: Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
Alias Symbols: D11moh34, MGC105799, RGD1310144
Protein Size: 258

Poids moléculaire: 28 kDa

ID gène: 287645

NCBI Accession: NM_001007804, NP_001007805

UniProt: Q5RK19