CLOCK anticorps (N-Term)

N° du produit ABIN2778091

Détail du produit anti-CLOCK anticorps

Antigène: CLOCK (Clock Homolog (Mouse) (CLOCK))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Mouton, Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLOCK est non-conjugé

Application: Western Blotting (WB)

Séquence: LFTVSCSKMS SIVDRDDSSI FDGLVEEDDK DKAKRVSRNK SEKKRRDQFN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CLOCK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CLOCK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 846 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CLOCK

Antigène: CLOCK (Clock Homolog (Mouse) (CLOCK))

Autre désignation: CLOCK (CLOCK Produits)

Synonymes: anticorps CG7391, anticorps CLK, anticorps CLOCK, anticorps Dmel\\CG7391, anticorps Jerk, anticorps Jrk, anticorps PAS1, anticorps bHLHe10, anticorps clk, anticorps clock, anticorps dCLK, anticorps dCLK/JRK, anticorps dCLOCK, anticorps dClck, anticorps dClk, anticorps dClock, anticorps dclk, anticorps jrk, anticorps Xclk, anticorps XClock, anticorps zCLOCK1, anticorps zfCLOCK1, anticorps 5330400M04Rik, anticorps KAT13D, anticorps bHLHe8, anticorps mKIAA0334, anticorps Clock, anticorps clock circadian regulator, anticorps clock homolog (mouse), anticorps clock circadian regulator a, anticorps circadian locomotor output cycles kaput, anticorps clock circadian regulator L homeolog, anticorps Clk, anticorps CLOCK, anticorps clock, anticorps clocka, anticorps Clock, anticorps clock.L

Sujet: CLOCK is a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KAT13D, KIAA0334, bHLHe8
Protein Interaction Partner: SIRT1, ARNTL, SOX2, TFAP4, UBC, ARNTL2, PER3, RXRA, RARA, KAT2B, EP300,
Protein Size: 846

Poids moléculaire: 95 kDa

ID gène: 9575

NCBI Accession: NM_004898, NP_004889

UniProt: O15516

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism