RBM14 anticorps (N-Term)

N° du produit ABIN2778973

Détail du produit anti-RBM14 anticorps

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM14 est non-conjugé

Application: Western Blotting (WB)

Séquence: YAFVHMEKEA DAKAAIAQLN GKEVKGKRIN VELSTKGQKK GPGLAVQSGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RBM14. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM14

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 669 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RBM14 (ABIN2778973)

Sui, Yang, Xiong, Zhang, Blanchard, Peiper, Dynan, Tuan, Ko: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." dans: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).

Détails sur RBM14

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Autre désignation: RBM14 (RBM14 Produits)

Sujet: RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
Alias Symbols: COAA, DKFZp779J0927, SIP, SYTIP1, PSP2, TMEM137
Protein Interaction Partner: UBC, SUMO2, SUMO3, CEP250, DROSHA, MDM2, SMURF2, RPA3, RPA2, RPA1, EZH2, BMI1, RNF2, SUZ12, EED, MAPK15, CDK15, CDK14, HDAC9, HDAC11, WHSC1, VCAM1, TRAF3, ITGA4, FN1, ESR1, ZC3H18, FTSJ3, RBM25, TRMT112, HP1BP3, PRPF19, RBMX, RSL1D1, PRPF6, HNRNPH1, RCC1,
Protein Size: 669

Poids moléculaire: 69 kDa

ID gène: 10432

NCBI Accession: NM_006328, NP_006319

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway