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STAU1/Staufen anticorps (N-Term)

STAU1 Reactivité: Humain, Rat, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779109
  • Antigène Voir toutes STAU1/Staufen (STAU1) Anticorps
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Épitope
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 66
    • 33
    • 31
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Humain, Rat, Cheval, Boeuf (Vache), Cobaye, Chien, Lapin
    Hôte
    • 62
    • 4
    Lapin
    Clonalité
    • 54
    • 12
    Polyclonal
    Conjugué
    • 31
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STAU1/Staufen est non-conjugé
    Application
    • 55
    • 21
    • 14
    • 13
    • 9
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    SQVQVQVQNP SAALSGSQIL NKNQSLLSQP LMSIPSTTSS LPSENAGRPI
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against STAU1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human STAU1
    Top Product
    Discover our top product STAU1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 577 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Autre désignation
    STAU1 (STAU1 Produits)
    Synonymes
    anticorps STAU1, anticorps DKFZp459A0124, anticorps CG5753, anticorps Dmel\\CG5753, anticorps Dmstau, anticorps STAU, anticorps Stau, anticorps Stauf, anticorps dStau, anticorps stau, anticorps XStau, anticorps XStau1, anticorps Staufen, anticorps Staufen1, anticorps MGC145034, anticorps 5830401L18Rik, anticorps AW549911, anticorps C85792, anticorps fi67e05, anticorps wu:fi67e05, anticorps zgc:77271, anticorps staufen double-stranded RNA binding protein 1, anticorps staufen, anticorps RNA binding protein homolog, anticorps staufen (RNA binding protein) homolog 1 (Drosophila), anticorps staufen double-stranded RNA binding protein 1 L homeolog, anticorps STAU1, anticorps stau, anticorps stau1, anticorps STAUFEN, anticorps Stau1, anticorps stau1.L
    Sujet
    This protein is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are haracterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translationStaufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
    Alias Symbols: FLJ25010, STAU
    Protein Interaction Partner: LONRF1, GLRX3, ZMAT3, NXT1, SPRTN, MATR3, EIF4A3, NUP155, PRDX6, NPEPPS, DDX23, DDX21, AIFM1, INA, ATP6V0D1, SART1, RPL14, AP3D1, CPNE3, IQGAP1, PABPC4, EIF3D, EIF3B, EIF3A, PRKRA, KHSRP, IRS4, SLC25A11, SMC1A, PABPN1, DDX39B, TUBA1A, MOGS, YWHAZ, XPO1, V
    Protein Size: 577
    Poids moléculaire
    63 kDa
    ID gène
    6780
    NCBI Accession
    NM_017453, NP_059347
    UniProt
    O95793
    Pathways
    Asymmetric Protein Localization
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