POU1F1 anticorps (Middle Region)

N° du produit ABIN2779561

Détail du produit anti-POU1F1 anticorps

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Chévre, Mouton, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU1F1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KRRTTISIAA KDALERHFGE QNKPSSQEIM RMAEELNLEK EVVRVWFCNR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human POU1F1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 291 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POU1F1

Antigène: POU1F1 (POU Class 1 Homeobox 1 (POU1F1))

Autre désignation: POU1F1 (POU1F1 Produits)

Synonymes: anticorps CPHD1, anticorps GHF-1, anticorps PIT1, anticorps POU1F1a, anticorps Pit-1, anticorps Hmp1, anticorps Pit1, anticorps Pit1-rs1, anticorps dw, anticorps dwarf, anticorps GHF1, anticorps GHF1A, anticorps PIT1Z, anticorps PIT-1, anticorps Pit-1*, anticorps pit1, anticorps pit-1, anticorps POU class 1 homeobox 1, anticorps POU domain, class 1, transcription factor 1, anticorps POU1F1, anticorps Pou1f1, anticorps pou1f1

Sujet: PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GHF-1, PIT1, Pit-1, Pit-1 beta, CPHD1, POU1F1a
Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
Protein Size: 291

Poids moléculaire: 33 kDa

ID gène: 5449

NCBI Accession: NM_000306, NP_000297

UniProt: P28069

Pathways: Regulation of Carbohydrate Metabolic Process