SUZ12 anticorps (Middle Region)

N° du produit ABIN2779689

Détail du produit anti-SUZ12 anticorps

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUZ12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Séquence: TGETNDKSTA PIAKPLATRN SESLHQENKP GSVKPTQTIA VKESLTTDLQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SUZ12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 739 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SUZ12

Antigène: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Autre désignation: SUZ12 (SUZ12 Produits)

Synonymes: anticorps fc31h10, anticorps im:7153578, anticorps si:dkey-10p5.2, anticorps suz12, anticorps wu:fc31h10, anticorps 2610028O16Rik, anticorps AI195385, anticorps AU016842, anticorps AW536442, anticorps D11Ertd530e, anticorps mKIAA0160, anticorps Xsuz12, anticorps chet9, anticorps jjaz1, anticorps CHET9, anticorps ChET 9 protein, anticorps JJAZ1, anticorps suz12l, anticorps zgc:100863, anticorps SUZ12 polycomb repressive complex 2b subunit, anticorps SUZ12 polycomb repressive complex 2 subunit, anticorps suppressor of zeste 12 homolog (Drosophila), anticorps SUZ12 polycomb repressive complex 2 subunit S homeolog, anticorps SUZ12 polycomb repressive complex 2a subunit, anticorps suz12b, anticorps Suz12, anticorps SUZ12, anticorps suz12.S, anticorps suz12a

Sujet: A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7,17)(p15,q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CHET9, JJAZ1, KIAA0160
Protein Interaction Partner: FBXW11, EZH2, BRCA1, CDK5RAP2, RBM22, LUC7L, NHP2, H2AFY2, C17orf85, NAT10, ATAD3A, HEATR1, PTCD3, CHCHD3, CDKAL1, DDX56, GDAP1, LUC7L3, SF3B6, LUC7L2, NOP58, LIMA1, CDC40, CRNKL1, HP1BP3, STOML2, TRA2A, RBM15B, REPIN1, PRPF19, AKAP8L, TBL2, DAZAP1, PHGDH
Protein Size: 739

Poids moléculaire: 83 kDa

ID gène: 23512

NCBI Accession: NM_015355, NP_056170

UniProt: Q15022