WWTR1 anticorps (N-Term)

N° du produit ABIN2779708

Détail du produit anti-WWTR1 anticorps

Antigène: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWTR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 400 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WWTR1

Antigène: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Autre désignation: WWTR1 (WWTR1 Produits)

Synonymes: anticorps WWTR1, anticorps TAZ, anticorps 2310058J06Rik, anticorps 2610021I22Rik, anticorps C78399, anticorps Taz, anticorps WW domain containing transcription regulator 1 L homeolog, anticorps WW domain containing transcription regulator 1, anticorps wwtr1.L, anticorps wwtr1, anticorps WWTR1, anticorps Wwtr1

Sujet: TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
Alias Symbols: DKFZP586I1419, TAZ
Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
Protein Size: 400

Poids moléculaire: 44 kDa

ID gène: 25937

NCBI Accession: NM_015472, NP_056287

UniProt: Q9GZV5

Pathways: Regulation of Lipid Metabolism by PPARalpha