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HIPK2 anticorps (Middle Region)

HIPK2 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2779735
  • Antigène Voir toutes HIPK2 Anticorps
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    Épitope
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 51
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval
    Hôte
    • 46
    • 6
    Lapin
    Clonalité
    • 44
    • 8
    Polyclonal
    Conjugué
    • 28
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIPK2 est non-conjugé
    Application
    • 30
    • 26
    • 16
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR
    Homologie
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%
    Attributs du produit
    This is a rabbit polyclonal antibody against HIPK2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1198 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Upadhyay, Bhadauriya, Ganesh: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." dans: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, (2016) (PubMed).

    Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." dans: Oncogene, Vol. 28, Issue 26, pp. 2446-55, (2009) (PubMed).

    Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." dans: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).

  • Antigène
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    Autre désignation
    HIPK2 (HIPK2 Produits)
    Synonymes
    anticorps HIPK2, anticorps cb1009, anticorps si:dkey-16j24.2, anticorps si:dkey-239k7.1, anticorps wu:fk56d12, anticorps pro0593, anticorps MGC146781, anticorps PRO0593, anticorps 1110014O20Rik, anticorps B230339E18Rik, anticorps Stank, anticorps PKM, anticorps homeodomain interacting protein kinase 2, anticorps serine/threonine kinase, anticorps homeodomain interacting protein kinase 2 L homeolog, anticorps HIPK2, anticorps Smp_000720, anticorps hipk2, anticorps hipk2.L, anticorps Hipk2
    Sujet
    HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
    Alias Symbols: DKFZp686K02111, FLJ23711, PRO0593
    Protein Interaction Partner: UBC, TP53, SIAH2, XAF1, AATF, SUMO1, MDM2, AXIN1, SIAH1, MBP, DAXX, MKNK1, MECP2, ZBTB4, HIPK2, DCAF7, DYRK1B, MAP3K1, DYRK1A, FBXO3, CBX4, SUMO2, SUMO3, PML, PAX6, CHMP4B, SENP2, SENP1, UBE2I, HIST2H2BE, CXCL1, SIAH1P1, WSB1, MYBL2, MYBL1, NLK, MAP3K7, M
    Protein Size: 1198
    Poids moléculaire
    120 kDa
    ID gène
    28996
    NCBI Accession
    NM_022740, NP_073577
    UniProt
    Q9H2X6
    Pathways
    Cycle Cellulaire
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