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NCOA2 anticorps (N-Term)

NCOA2 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2780788
  • Antigène Voir toutes NCOA2 Anticorps
    NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
    Épitope
    • 15
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 56
    • 14
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Porc
    Hôte
    • 52
    • 3
    • 1
    Lapin
    Clonalité
    • 53
    • 3
    Polyclonal
    Conjugué
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NCOA2 est non-conjugé
    Application
    • 39
    • 13
    • 13
    • 10
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MSGMGENTSD PSRAETRKRK ECPDQLGPSP KRNTEKRNRE QENKYIEELA
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against NCOA2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human NCOA2
    Top Product
    Discover our top product NCOA2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1464 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Strehl, Nebral, König, Harbott, Strobl, Ratei, Struski, Bielorai, Lessard, Zimmermann, Haas, Izraeli: "ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 4, pp. 977-83, (2008) (PubMed).

  • Antigène
    NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
    Autre désignation
    NCOA2 (NCOA2 Produits)
    Synonymes
    anticorps GRIP1, anticorps KAT13C, anticorps NCoA-2, anticorps SRC2, anticorps TIF2, anticorps bHLHe75, anticorps 9530095N19, anticorps D1Ertd433e, anticorps GRIP-1, anticorps Grip1, anticorps SRC-2, anticorps TIF-2, anticorps tif2, anticorps wu:fc41a10, anticorps wu:fe26a11, anticorps Tif2, anticorps NCOA2, anticorps XTIF2, anticorps bhlhe75, anticorps grip1, anticorps kat13c, anticorps src2, anticorps ncoa2-A, anticorps nuclear receptor coactivator 2, anticorps nuclear receptor coactivator 2 S homeolog, anticorps NCOA2, anticorps Ncoa2, anticorps ncoa2, anticorps LOC100089041, anticorps ncoa2.S
    Sujet
    NCOA2 is the transcriptional coactivator for steroid receptors and nuclear receptors. NCOA2 is the coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). NCOA2 is required with NCOA1 to control energy balance
    Alias Symbols: GRIP1, KAT13C, MGC138808, NCoA-2, TIF2, SRC2, bHLHe75
    Protein Interaction Partner: VDR, PSMB9, PPARG, ESR1, PML, UBC, TP53, TAF9, Pias3, tat, THRB, NR3C1, EP300, NR1I2, RXRA, RARA, CREBBP, AHR, KANK2, MAGEA11, NCOA1, HHV8GK18_gp81, ESR2, PGR, SUMO2, CAD, ATR, HSPA2, CC2D1A, UBR5, TBK1, WDHD1, USO1, STAT6, NCOA3, THRA, CDK4, CCND3, EID1,
    Protein Size: 1464
    Poids moléculaire
    159 kDa
    ID gène
    10499
    NCBI Accession
    NM_006540, NP_006531
    UniProt
    Q15596
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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