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PIAS1 anticorps (N-Term)

PIAS1 Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2780997
  • Antigène Voir toutes PIAS1 Anticorps
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    Épitope
    • 11
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 49
    • 11
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Cobaye, Poisson zèbre (Danio rerio)
    Hôte
    • 46
    • 4
    Lapin
    Clonalité
    • 46
    • 4
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIAS1 est non-conjugé
    Application
    • 41
    • 25
    • 24
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MADSAELKQM VMSLRVSELQ VLLGYAGRNK HGRKHELLTK ALHLLKAGCS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PIAS1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS1
    Top Product
    Discover our top product PIAS1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 651 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    Autre désignation
    PIAS1 (PIAS1 Produits)
    Synonymes
    anticorps 2900068C24Rik, anticorps Ddxbp1, anticorps GBP, anticorps DDXBP1, anticorps GU/RH-II, anticorps ZMIZ3, anticorps ddxbp1, anticorps gbp, anticorps pias, anticorps pias1-A, anticorps xPAIS1, anticorps xPIAS1, anticorps zmiz3, anticorps protein inhibitor of activated STAT 1, anticorps protein inhibitor of activated STAT, 1, anticorps protein inhibitor of activated STAT, 1a, anticorps protein inhibitor of activated STAT 1 L homeolog, anticorps PIAS1, anticorps Pias1, anticorps pias1a, anticorps pias1.L
    Sujet
    PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3
    Protein Interaction Partner: STAT1, TRIM63, TRIM55, CEP250, PRDM1, SUMO1, L3MBTL2, CBS, SHFM1, SUMO2, SUMO3, SOX2, CHUK, SPOP, YWHAZ, UBC, SKIL, SGTA, ATXN1, SMAD7, SMAD4, SMAD1, HTT, PRPF40A, PPP1CC, BARD1, PAXIP1, NR1H2, PPARGC1A, NR1H3, PPARGC1B, RAD54L2, ZMYND11, UBD, PLAG1, MYB,
    Protein Size: 651
    Poids moléculaire
    72 kDa
    ID gène
    8554
    NCBI Accession
    NM_016166, NP_057250
    UniProt
    O75925
    Pathways
    Signalistation JAK/STAT, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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