COQ8A anticorps (N-Term)

N° du produit ABIN2783345

Détail du produit anti-COQ8A anticorps

Antigène: COQ8A (Coenzyme Q8A (COQ8A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COQ8A est non-conjugé

Application: Western Blotting (WB)

Séquence: FANPRDSFSA MGFQRRFFHQ DQSPVGGLTA EDIEKARQAK ARPENKQHKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%

Attributs du produit: This is a rabbit polyclonal antibody against CABC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CABC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 647 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-COQ8A (ABIN2783345)

Lagier-Tourenne, Tazir, López, Quinzii, Assoum, Drouot, Busso, Makri, Ali-Pacha, Benhassine, Anheim, Lynch, Thibault, Plewniak, Bianchetti, Tranchant, Poch, DiMauro, Mandel, Barros, Hirano, Koenig: "ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency." dans: American journal of human genetics, Vol. 82, Issue 3, pp. 661-72, (2008) (PubMed).

Détails sur COQ8A

Antigène: COQ8A (Coenzyme Q8A (COQ8A))

Autre désignation: CABC1 (COQ8A Produits)

Synonymes: anticorps ARCA2, anticorps CABC1, anticorps COQ10D4, anticorps COQ8, anticorps SCAR9, anticorps 4632432J16Rik, anticorps AI462003, anticorps Cabc1, anticorps mKIAA0451, anticorps cabc1, anticorps Adck3, anticorps adck4, anticorps si:dkey-114g7.2, anticorps coenzyme Q8A, anticorps aarF domain containing kinase 3, anticorps coenzyme Q8B, anticorps COQ8A, anticorps Coq8a, anticorps coq8a, anticorps ADCK3, anticorps coq8b

Sujet: CABC1 is a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis.This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.
Alias Symbols: ADCK3, COQ8, MGC4849, ARCA2, CABC1, SCAR9
Protein Interaction Partner: TMEM239, REEP6, TMEM159, AGTRAP, TFIP11, RABAC1, VCP, UBC, IRAK2, IRAK1, ICT1, COQ8,
Protein Size: 647

Poids moléculaire: 72 kDa

ID gène: 56997

NCBI Accession: NM_020247, NP_064632

UniProt: Q8NI60