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HSD3B7 anticorps (Middle Region)

HSD3B7 Reactivité: Humain, Rat, Souris, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783973
  • Antigène Voir toutes HSD3B7 Anticorps
    HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
    Épitope
    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Middle Region
    Reactivité
    • 21
    • 21
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye
    Hôte
    • 35
    • 1
    Lapin
    Clonalité
    • 36
    Polyclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HSD3B7 est non-conjugé
    Application
    • 15
    • 13
    • 13
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    QGTRNVIEAC VQTGTRFLVY TSSMEVVGPN TKGHPFYRGN EDTPYEAVHR
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against HSD3B7. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human HSD3B7
    Top Product
    Discover our top product HSD3B7 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 369 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
    Autre désignation
    HSD3B7 (HSD3B7 Produits)
    Synonymes
    anticorps CBAS1, anticorps PFIC4, anticorps SDR11E3, anticorps AI195443, anticorps BB098564, anticorps Cca2, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7, anticorps HSD3B7, anticorps Hsd3b7
    Sujet
    This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: PFIC4, CBAS1, SDR11E3
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-1, KRTAP10-9, KRTAP4-2, SPRY2, UBC, KRTAP10-7, DAPP1, PYGL, ICAM1, Hoxa1,
    Protein Size: 369
    Poids moléculaire
    41 kDa
    ID gène
    80270
    NCBI Accession
    NM_025193, NP_079469
    UniProt
    Q9H2F3
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