HSD3B7 anticorps (Middle Region)
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- Antigène Voir toutes HSD3B7 Anticorps
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cheval, Lapin, Boeuf (Vache), Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HSD3B7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QGTRNVIEAC VQTGTRFLVY TSSMEVVGPN TKGHPFYRGN EDTPYEAVHR
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against HSD3B7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HSD3B7
- Top Product
- Discover our top product HSD3B7 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 369 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
- Autre désignation
- HSD3B7 (HSD3B7 Produits)
- Synonymes
- anticorps CBAS1, anticorps PFIC4, anticorps SDR11E3, anticorps AI195443, anticorps BB098564, anticorps Cca2, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7, anticorps HSD3B7, anticorps Hsd3b7
- Sujet
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This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PFIC4, CBAS1, SDR11E3
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-1, KRTAP10-9, KRTAP4-2, SPRY2, UBC, KRTAP10-7, DAPP1, PYGL, ICAM1, Hoxa1,
Protein Size: 369 - Poids moléculaire
- 41 kDa
- ID gène
- 80270
- NCBI Accession
- NM_025193, NP_079469
- UniProt
- Q9H2F3
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