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CYP3A4 anticorps (Middle Region)

CYP3A4 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Mouton, Chévre, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784528
  • Antigène Voir toutes CYP3A4 Anticorps
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Épitope
    • 16
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 88
    • 37
    • 35
    • 17
    • 15
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Mouton, Chévre, Cheval
    Hôte
    • 78
    • 9
    • 1
    Lapin
    Clonalité
    • 73
    • 15
    Polyclonal
    Conjugué
    • 49
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CYP3A4 est non-conjugé
    Application
    • 71
    • 24
    • 21
    • 20
    • 19
    • 16
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Séquence
    MIPSYALHRD PKYWTEPEKF LPERFSKKNK DNIDPYIYTP FGSGPRNCIG
    Homologie
    Cow: 86%, Dog: 85%, Goat: 86%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against CYP3A4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human CYP3A4
    Top Product
    Discover our top product CYP3A4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 503 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: "Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." dans: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).

  • Antigène
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Autre désignation
    CYP3A4 (CYP3A4 Produits)
    Synonymes
    anticorps CP33, anticorps CP34, anticorps CYP3A, anticorps CYP3A3, anticorps CYPIIIA3, anticorps CYPIIIA4, anticorps HLP, anticorps NF-25, anticorps P450C3, anticorps P450PCN1, anticorps MGC108372, anticorps CYP3A80, anticorps CYP3A4, anticorps CYP3A21, anticorps CYPIIIA21, anticorps CYP3A12, anticorps cytochrome P450 family 3 subfamily A member 4, anticorps cytochrome P450 family 3 subfamily A member 43, anticorps cytochrome P450 3A4, anticorps cytochrome P450, subfamily IIIA, polypeptide 4, anticorps cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, anticorps cytochrome P450, family 3, subfamily A, polypeptide 4, anticorps CYP3A4, anticorps CYP3A43, anticorps PTRG_01782, anticorps PTRG_06060, anticorps cyp3a4
    Sujet
    This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot
    Alias Symbols: CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1, CYPIIIA3, CYPIIIA4
    Protein Interaction Partner: UBC, PRKCA, PRKACA, PGRMC1, POR, GK, CYB5A, STUB1, AMFR, UGT2B7,
    Protein Size: 503
    Poids moléculaire
    57 kDa
    ID gène
    1576
    NCBI Accession
    NM_017460, NP_059488
    UniProt
    P08684
    Pathways
    Steroid Hormone Biosynthesis
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