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RDH12 anticorps (Middle Region)

RDH12 Reactivité: Humain, Porc, Rat, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785175
  • Antigène Voir toutes RDH12 Anticorps
    RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
    Épitope
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Porc, Rat, Chien
    Hôte
    • 12
    • 3
    Lapin
    Clonalité
    • 13
    • 2
    Polyclonal
    Conjugué
    • 11
    • 2
    • 1
    • 1
    Cet anticorp RDH12 est non-conjugé
    Application
    • 8
    • 8
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    HIGKIPFHDL QSEKRYSRGF AYCHSKLANV LFTRELAKRL QGTGVTTYAV
    Homologie
    Dog: 93%, Human: 100%, Pig: 79%, Rat: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human RDH12
    Top Product
    Discover our top product RDH12 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 316 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sun, Gerth, Maeda, Lodowski, Van Der Kraak, Saperstein, Héon, Palczewski: "Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations." dans: Vision research, Vol. 47, Issue 15, pp. 2055-66, (2007) (PubMed).

  • Antigène
    RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
    Autre désignation
    RDH12 (RDH12 Produits)
    Synonymes
    anticorps wu:fj43a10, anticorps zgc:92430, anticorps A930033N07Rik, anticorps LCA13, anticorps LCA3, anticorps RP53, anticorps SDR7C2, anticorps DSSDR2, anticorps retinol dehydrogenase 12 (all-trans/9-cis/11-cis), anticorps retinol dehydrogenase 12, anticorps Retinol dehydrogenase 12, anticorps RDH12, anticorps rdh12, anticorps MAV_1968, anticorps CC1G_02720, anticorps Bm1_36660, anticorps PTRG_03574, anticorps PTRG_05326, anticorps PTRG_08067, anticorps LOC100282710, anticorps LOC100285880, anticorps LOC100226769, anticorps Rdh12
    Sujet
    RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
    Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
    Protein Interaction Partner: RBPMS, UBC, ANXA8L1, MAP1LC3A, BUB1,
    Protein Size: 316
    Poids moléculaire
    35 kDa
    ID gène
    145226
    NCBI Accession
    NM_152443, NP_689656
    UniProt
    Q96NR8
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