KHDRBS2 anticorps (N-Term)

N° du produit ABIN2785231

Détail du produit anti-KHDRBS2 anticorps

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: EEIEKFQGSD GKKEDEEKKY LDVISNKNIK LSERVLIPVK QYPKFNFVGK

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KHDRBS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 349 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KHDRBS2

Antigène: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Autre désignation: KHDRBS2 (KHDRBS2 Produits)

Synonymes: anticorps slm1, anticorps slm-1, anticorps MGC145973, anticorps ba535f17.1, anticorps zgc:153588, anticorps SLM-1, anticorps SLM1, anticorps bA535F17.1, anticorps 6330586C16Rik, anticorps Slim1, anticorps Slm1, anticorps KH RNA binding domain containing, signal transduction associated 2, anticorps KH domain containing, RNA binding, signal transduction associated 2, anticorps KHDRBS2, anticorps khdrbs2, anticorps Khdrbs2

Sujet: KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: HBZ, DOCK2, CIRBP, TYMSOS, LINC01018, KHDRBS2, ZFC3H1, CATSPER1, YTHDC1, PRR3, NABP1, AEN, NCOA5, NPDC1, RBMX, PRPF31, CHTOP, HNRNPR, MTA1, TYK2, SULT1A3, SPG7, SDCBP, RBM3, PTK6, UBC, KHDRBS3, HNRNPK, LYN, HNRNPC, HNRNPA2B1, HNRNPA1, FGG, FGB, FGA, DSG1,
Protein Size: 349

Poids moléculaire: 39 kDa

ID gène: 202559

NCBI Accession: NM_152688, NP_689901

UniProt: Q5VWX1