TRIB2 anticorps (Middle Region)

N° du produit ABIN2786174

Détail du produit anti-TRIB2 anticorps

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: YPFHDIEPSS LFSKIRRGQF NIPETLSPKA KCLIRSILRR EPSERLTSQE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TRIB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 343 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIB2

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Autre désignation: TRIB2 (TRIB2 Produits)

Synonymes: anticorps TRIB2, anticorps Trb2, anticorps Xtrbl, anticorps gs3955, anticorps c5fw, anticorps trb2, anticorps xtrb2, anticorps TRB2, anticorps C5FW, anticorps GS3955, anticorps TRB-2, anticorps AW319517, anticorps RGD1564451, anticorps tribbles pseudokinase 2, anticorps tribbles pseudokinase 2 S homeolog, anticorps TRIB2, anticorps trib2, anticorps trib2.S, anticorps Trib2

Sujet: TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.
Alias Symbols: GS3955, TRB2, C5FW
Protein Interaction Partner: RFWD2, SMURF1, BTRC, PRMT6, UBC, RPS6KB1, SLAMF7, APP, UBQLN4,
Protein Size: 343

Poids moléculaire: 39 kDa

ID gène: 28951

NCBI Accession: NM_021643, NP_067675

UniProt: Q92519