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BLMH anticorps (Middle Region)

BLMH Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Cheval, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2786515
  • Antigène Voir toutes BLMH Anticorps
    BLMH (Bleomycin Hydrolase (BLMH))
    Épitope
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 28
    • 28
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Cobaye, Boeuf (Vache), Cheval, Lapin
    Hôte
    • 41
    • 11
    • 1
    Lapin
    Clonalité
    • 45
    • 8
    Polyclonal
    Conjugué
    • 24
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BLMH est non-conjugé
    Application
    • 46
    • 13
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    EYLSNMVGGR KTLYNNQPID FLKKMVAASI KDGEAVWFGC DVGKHFNSKL
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Attributs du produit
    This is a rabbit polyclonal antibody against BLMH. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human BLMH
    Top Product
    Discover our top product BLMH Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 455 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    BLMH (Bleomycin Hydrolase (BLMH))
    Autre désignation
    BLMH (BLMH Produits)
    Synonymes
    anticorps AI035728, anticorps Bh, anticorps Bmh, anticorps wu:fb13c01, anticorps zgc:66261, anticorps bh, anticorps bmh, anticorps BH, anticorps BMH, anticorps bleomycin hydrolase, anticorps Bleomycin hydrolase, anticorps bleomycin hydrolase S homeolog, anticorps BLMH, anticorps pepC, anticorps LOC5569945, anticorps Apre_0140, anticorps Apar_0899, anticorps Smon_1289, anticorps Kfla_1242, anticorps Snas_3912, anticorps BLJ_1941, anticorps Olsu_1085, anticorps PGTDC60_0106, anticorps Blmh, anticorps blmh, anticorps blmh.S
    Sujet
    The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BH, BMH
    Protein Interaction Partner: NUDT12, WDYHV1, BLMH, UBC, ZBTB1, SH3GLB2, LZTFL1, GORASP2, PES1, GTF2A1, AP1M2, CYP2C8, RNF32, ECSIT, MAST1, COPS5, CUL4B, SUMO2, PDPK1, Fam134a, USP53, KBTBD7, RPL11, UBE2I, TRIO, RPL29, APP,
    Protein Size: 455
    Poids moléculaire
    52 kDa
    ID gène
    642
    NCBI Accession
    NM_000386, NP_000377
    UniProt
    Q13867
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