GOPC anticorps (Middle Region)
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- Antigène Voir toutes GOPC Anticorps
- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GOPC est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RNDLKRPMQA PPGHDQDSLK KSQGVGPIRK VLLLKEDHEG LGISITGGKE
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GOPC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human GOPC
- Top Product
- Discover our top product GOPC Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 454 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
- Autre désignation
- GOPC (GOPC Produits)
- Synonymes
- anticorps DKFZp459H2130, anticorps 2210402P09Rik, anticorps AI844555, anticorps CAL, anticorps FIG, anticorps GOPC1, anticorps PIST, anticorps fe38f01, anticorps wu:fe38f01, anticorps zgc:56254, anticorps zgc:65853, anticorps dJ94G16.2, anticorps cal, anticorps gopc1, anticorps pist, anticorps golgi associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing S homeolog, anticorps GOPC, anticorps Gopc, anticorps gopc, anticorps gopc.S
- Sujet
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GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].
Alias Symbols: CAL, FIG, GOPC1, PIST, dJ94G16.2
Protein Interaction Partner: BATF, SSNA1, VTN, MYLK, HCK, FOSL2, DPYD, RPL13AP17, C17orf67, ZSCAN1, LCLAT1, FAM9B, ZBTB49, ZNF564, SPATA8, RNF183, MORN4, MYOCD, MUM1, ZNF587, SLC25A18, CCDC102B, AKIRIN1, MRPL1, SEMA4G, RNF220, FAM90A1, PID1, ZNF581, CERCAM, RHOQ, PARK7, STARD3, HSF1,
Protein Size: 454 - Poids moléculaire
- 50 kDa
- ID gène
- 57120
- NCBI Accession
- NM_001017408, NP_001017408
- UniProt
- Q9HD26
- Pathways
- Maintenance of Protein Location, Asymmetric Protein Localization
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