GOPC anticorps (Middle Region)

N° du produit ABIN2786579

Détail du produit anti-GOPC anticorps

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOPC est non-conjugé

Application: Western Blotting (WB)

Séquence: RNDLKRPMQA PPGHDQDSLK KSQGVGPIRK VLLLKEDHEG LGISITGGKE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GOPC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GOPC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 454 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GOPC

Antigène: GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))

Autre désignation: GOPC (GOPC Produits)

Synonymes: anticorps DKFZp459H2130, anticorps 2210402P09Rik, anticorps AI844555, anticorps CAL, anticorps FIG, anticorps GOPC1, anticorps PIST, anticorps fe38f01, anticorps wu:fe38f01, anticorps zgc:56254, anticorps zgc:65853, anticorps dJ94G16.2, anticorps cal, anticorps gopc1, anticorps pist, anticorps golgi associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing, anticorps golgi-associated PDZ and coiled-coil motif containing S homeolog, anticorps GOPC, anticorps Gopc, anticorps gopc, anticorps gopc.S

Sujet: GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].
Alias Symbols: CAL, FIG, GOPC1, PIST, dJ94G16.2
Protein Interaction Partner: BATF, SSNA1, VTN, MYLK, HCK, FOSL2, DPYD, RPL13AP17, C17orf67, ZSCAN1, LCLAT1, FAM9B, ZBTB49, ZNF564, SPATA8, RNF183, MORN4, MYOCD, MUM1, ZNF587, SLC25A18, CCDC102B, AKIRIN1, MRPL1, SEMA4G, RNF220, FAM90A1, PID1, ZNF581, CERCAM, RHOQ, PARK7, STARD3, HSF1,
Protein Size: 454

Poids moléculaire: 50 kDa

ID gène: 57120

NCBI Accession: NM_001017408, NP_001017408

UniProt: Q9HD26

Pathways: Maintenance of Protein Location, Asymmetric Protein Localization