Acylglycerol Kinase anticorps (N-Term)

N° du produit ABIN2787097

Détail du produit anti-Acylglycerol Kinase anticorps

Antigène: Acylglycerol Kinase (AGK)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acylglycerol Kinase est non-conjugé

Application: Western Blotting (WB)

Séquence: DNLLRRAACQ EAQVFGNQLI PPNAQVKKAT VFLNPAACKG KARTLFEKNA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AGK

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 422 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Acylglycerol Kinase

Antigène: Acylglycerol Kinase (AGK)

Autre désignation: AGK (AGK Produits)

Synonymes: anticorps mulk, anticorps CATC5, anticorps CTRCT38, anticorps MTDPS10, anticorps MULK, anticorps 2610037M15Rik, anticorps 6720408I04Rik, anticorps AI465370, anticorps Mulk, anticorps RGD1562046, anticorps fi38e09, anticorps wu:fi38e09, anticorps zgc:55462, anticorps acylglycerol kinase, anticorps acylglycerol kinase S homeolog, anticorps AGK, anticorps agk, anticorps LOC100165096, anticorps Agk, anticorps agk.S

Sujet: AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422

Poids moléculaire: 47 kDa

ID gène: 55750

NCBI Accession: NM_018238, NP_060708

UniProt: Q53H12