RCAN1 anticorps (N-Term)
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- Antigène Voir toutes RCAN1 Anticorps
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RCAN1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS
- Homologie
- Dog: 93%, Human: 100%, Mouse: 77%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against RCAN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RCAN1
- Top Product
- Discover our top product RCAN1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 252 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Autre désignation
- RCAN1 (RCAN1 Produits)
- Synonymes
- anticorps ADAPT78, anticorps CSP1, anticorps DSC1, anticorps DSCR1, anticorps MCIP1, anticorps RCN1, anticorps RCAN1, anticorps 2410048A02Rik, anticorps AA408855, anticorps AI429645, anticorps AL024459, anticorps AV028423, anticorps Adapt78, anticorps CALP1L, anticorps Dscr1, anticorps Mcip1, anticorps dscr1, anticorps rcan1, anticorps wu:fr92c05, anticorps adapt78, anticorps csp1, anticorps dsc1, anticorps mcip1, anticorps MGC53636, anticorps rcn1, anticorps MGC69428, anticorps regulator of calcineurin 1, anticorps regulator of calcineurin 1b, anticorps regulator of calcineurin 1 L homeolog, anticorps Down syndrome critical region gene 1, anticorps RCAN1, anticorps Rcan1, anticorps rcan1b, anticorps rcan1.L, anticorps dscr1, anticorps rcan1
- Sujet
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: UBC, PPP3CA, NEDD8, APP, FBXW11, BTRC, FBXW4, TOLLIP, TRAF6, IRAK1, HSP90AA1, STAT2, GSK3B, MAP3K3, MAPK3, UXT,
Protein Size: 252 - Poids moléculaire
- 28 kDa
- ID gène
- 1827
- NCBI Accession
- NM_004414, NP_004405
- UniProt
- P53805
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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