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MED14 anticorps (Middle Region)

MED14 Reactivité: Humain, Souris, Lapin WB, ChIP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787568
  • Antigène Voir toutes MED14 Anticorps
    MED14 (Mediator Complex Subunit 14 (MED14))
    Épitope
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 23
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Lapin
    Hôte
    • 31
    • 3
    Lapin
    Clonalité
    • 31
    • 3
    Polyclonal
    Conjugué
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MED14 est non-conjugé
    Application
    • 22
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Séquence
    AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
    Homologie
    Human: 100%, Mouse: 79%, Rabbit: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human MED14
    Top Product
    Discover our top product MED14 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1454 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MED14 (Mediator Complex Subunit 14 (MED14))
    Autre désignation
    MED14 (MED14 Produits)
    Synonymes
    anticorps CG12031, anticorps Dmel\\CG12031, anticorps Med14, anticorps Trap170, anticorps dTRAP170, anticorps p160, anticorps EXLM1, anticorps crsp150, anticorps crsp2, anticorps trap170, anticorps wu:fd21c05, anticorps wu:fk28h11, anticorps CRSP2, anticorps NV18605, anticorps CRSP150, anticorps CSRP, anticorps CXorf4, anticorps DRIP150, anticorps RGR1, anticorps TRAP170, anticorps 9930001L01Rik, anticorps AU041628, anticorps Crsp2, anticorps ENSMUSG00000073278, anticorps Gm641, anticorps ORF1, anticorps RGD1560170, anticorps Mediator complex subunit 14, anticorps mediator complex subunit 14, anticorps mediator of RNA polymerase II transcription subunit 14, anticorps transcriptional regulation, anticorps MED14, anticorps med14, anticorps LOC100113592, anticorps Med14, anticorps RGR1
    Sujet
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
    Alias Symbols: CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, MGC104513, RGR1, TRAP170
    Protein Interaction Partner: UBC, HECW2, CDK8, CDK19, MED12, ESR1, MED19, MED26, PPARG, FBXW7, EPAS1, MED11, MED8, MED29, MED18, MED4, PPP6R1, MED16, MED13, MED24, MED27, MED17, MED21, MED1, CTDP1, SREBF1, DCTN1, ACTN2, ACTN1, MED10, UACA, NECAB2, MED25, MED15, CRSP5, MED7, MED23, VD
    Protein Size: 1454
    Poids moléculaire
    160 kDa
    ID gène
    9282
    NCBI Accession
    NM_004229, NP_004220
    UniProt
    O60244
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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