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LRP1 anticorps (Middle Region)

LRP1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787740
  • Antigène Voir toutes LRP1 Anticorps
    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
    Épitope
    • 16
    • 13
    • 11
    • 11
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 102
    • 55
    • 53
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 93
    • 28
    • 1
    Lapin
    Clonalité
    • 86
    • 36
    Polyclonal
    Conjugué
    • 45
    • 13
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LRP1 est non-conjugé
    Application
    • 65
    • 45
    • 37
    • 33
    • 21
    • 15
    • 15
    • 14
    • 14
    • 9
    • 9
    • 7
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    ATYLSGAQVS TITPTSTRQT TAMDFSYANE TVCWVHVGDS AAQTQLKCAR
    Attributs du produit
    This is a rabbit polyclonal antibody against LRP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human LRP1
    Top Product
    Discover our top product LRP1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 439 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hentschke, Poli-de-Figueiredo, da Costa, Kurlak, Williams, Mistry: "Is the atherosclerotic phenotype of preeclamptic placentas due to altered lipoprotein concentrations and placental lipoprotein receptors? Role of a small-for-gestational-age phenotype." dans: Journal of lipid research, Vol. 54, Issue 10, pp. 2658-64, (2013) (PubMed).

    Gu, Wei, Monnot, Fontanilla, Behl, Farlow, Zheng, Du: "Lead exposure increases levels of ?-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice." dans: Neuroscience letters, Vol. 490, Issue 1, pp. 16-20, (2011) (PubMed).

    Behl, Zhang, Monnot, Jiang, Zheng: "Increased beta-amyloid levels in the choroid plexus following lead exposure and the involvement of low-density lipoprotein receptor protein-1." dans: Toxicology and applied pharmacology, Vol. 240, Issue 2, pp. 245-54, (2009) (PubMed).

  • Antigène
    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
    Autre désignation
    LRP1 (LRP1 Produits)
    Synonymes
    anticorps A2MR, anticorps APOER, anticorps APR, anticorps CD91, anticorps IGFBP3R, anticorps LRP, anticorps LRP1A, anticorps TGFBR5, anticorps A2mr, anticorps AI316852, anticorps Lrp, anticorps LRP-1, anticorps LDL receptor related protein 1, anticorps prolow-density lipoprotein receptor-related protein 1, anticorps low density lipoprotein receptor-related protein 1, anticorps LRP1, anticorps Lrp1, anticorps LOC100414789
    Sujet
    Low-density lipoprotein receptor-related protein 1 (.-2-macroglobulin receptor, LRP1) is a multifunctional endocytic receptor with an important role in regulating the activity of proteinases in the extracellular matrix. It is also involved in intracellular signaling and the subcellular translocation of preassembled signaling complexes from the plasma membrane.
    Alias Symbols: APR, LRP, A2MR, CD91, APOER, TGFBR5, IGFBP3R
    Protein Interaction Partner: UBC, COPS5, APP, RANBP9, SKIL, CHFR, CUBN, FBXO6, ANKS1B, RIC8B, PID1, CC2D1A, MAPRE1, HNRNPDL, MAPK8IP1, SNRNP70, APOE, CACNA1A, USP3, CAV1, MMP14, SHC1, MMP13, SERPINA1, F9, F8, LPL, HSP90B1, SRC, PDGFB, THBS1, SCN3A, PLAUR, PLAT, SERPINE1, MDK, LIPC, L
    Protein Size: 439
    Poids moléculaire
    48 kDa
    ID gène
    4035
    NCBI Accession
    NM_002332
    UniProt
    Q07954
    Pathways
    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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