TIMP1 anticorps (N-Term)

N° du produit ABIN2787966

Détail du produit anti-TIMP1 anticorps

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Chien, Cheval, Mouton, Boeuf (Vache), Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QRYEIKMTKM YKGFQALGDA ADIRFVYTPA MESVCGYFHR SHNRSEEFLI

Homologie: Cow: 93%, Dog: 86%, Goat: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TIMP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TIMP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TIMP1

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: TIMP1 (TIMP1 Produits)

Synonymes: anticorps TIMP-1, anticorps TIMP1, anticorps DKFZp468A0912, anticorps CLGI, anticorps EPA, anticorps EPO, anticorps HCI, anticorps TIMP, anticorps Timp, anticorps Clgi, anticorps TIMP metallopeptidase inhibitor 1, anticorps tissue inhibitor of metalloproteinase 1, anticorps TIMP1, anticorps Timp1

Sujet: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Alias Symbols: CLGI, EPA, HCI, TIMP
Protein Interaction Partner: UBC, FBXO6, MYOC, ZBTB16, RECQL5, ECH1, EEF1B2, MMP3, CD63, MMP2, MMP1,
Protein Size: 207

Poids moléculaire: 23 kDa

ID gène: 7076

NCBI Accession: NM_003254, NP_003245

UniProt: Q6FGX5