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MME anticorps (C-Term)

MME Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789467
  • Antigène Voir toutes MME Anticorps
    MME (Membrane Metallo-Endopeptidase (MME))
    Épitope
    • 16
    • 13
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 213
    • 57
    • 49
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye
    Hôte
    • 110
    • 109
    • 2
    Lapin
    Clonalité
    • 116
    • 104
    • 2
    Polyclonal
    Conjugué
    • 108
    • 19
    • 19
    • 14
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MME est non-conjugé
    Application
    • 132
    • 101
    • 80
    • 69
    • 38
    • 29
    • 22
    • 21
    • 13
    • 13
    • 10
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against MME. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product MME Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 750 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MME (Membrane Metallo-Endopeptidase (MME))
    Autre désignation
    MME (MME Produits)
    Synonymes
    anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme
    Classe de substances
    Chemical
    Sujet
    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.
    Alias Symbols: CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE
    Protein Interaction Partner: MME, NPPA, AGT, HDAC8, UBC, NDRG1, FAM83F, RGPD6, POTEI, TUBB8, UBAC2, KBTBD3, MTDH, ITFG3, ARMC10, FAHD1, CDK5RAP3, MRPL44, NUCKS1, MRPS25, LAMTOR1, DNAJB12, SDF4, METTL7A, NNT, CPSF6, PDIA5, RUVBL2, TM9SF1, MRVI1, CLEC4M, ZMPSTE24, RBM39, ATP5J2, SLC9A3
    Protein Size: 750
    Poids moléculaire
    83 kDa
    ID gène
    4311
    NCBI Accession
    NM_007287, NP_009218
    UniProt
    P08473
    Pathways
    Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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