LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (Middle Region) anticorps

Détails pour le produit réf. ABIN2789689, Fournisseur: Connectez-vous pour afficher
Antigène
  • PINCH
  • PINCH-1
  • PINCH1
  • Pinch1
  • RGD1560732
  • LIMS3
  • LIMS3L
  • 2310016J22Rik
  • 4921524A02Rik
  • AI507642
  • AU021743
  • AW551584
  • C430041B13Rik
  • Lims1l
  • LIM zinc finger domain containing 1
  • LIM and senescent cell antigen-like domains 1
  • LIMS1
  • Lims1
Épitope
Middle Region
4
4
3
3
2
1
Reactivité
Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Humain, Souris, Lapin, Rat (Rattus), Poisson Zèbre
53
31
31
4
3
3
3
3
3
3
2
2
2
2
Hôte
Lapin
42
12
Clonalité
Polyclonal
Conjugué
Inconjugué
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
38
19
14
13
9
8
6
5
3
1
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène The immunogen is a synthetic peptide directed towards the middle region of Human LIMS1
Blocking Peptide Blocking peptide for this product available: ABIN979327
Séquence HLCRPCHNRE KARGLGKYIC QKCHAIIDEQ PLIFKNDPYH PDHFNCANCG
Homologie Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Attributs du produit This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
Purification Affinity Purified
Autre désignation LIMS1 (LIMS1 Antibody Extrait)
Sujet The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PINCH, PINCH1
Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
Protein Size: 387
Poids moléculaire 44 kDa
ID gène 3987
NCBI Accession NM_001193485, NP_001180414
UniProt B7Z7R3
Domaine de recherche Cancer, Angiogenesis
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 387 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (Middle Region) antibody (ABIN2789689) WB Suggested Anti-LIMS1 Antibody Titration: 1.0 ug/ml Positive Control: U937 Whole Cell
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