GPBAR1 anticorps (C-Term)

N° du produit ABIN2789752

Détail du produit anti-GPBAR1 anticorps

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPBAR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ

Homologie: Human: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GPBAR1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 330 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPBAR1

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Autre désignation: GPBAR1 (GPBAR1 Produits)

Synonymes: anticorps BG37, anticorps GPCR19, anticorps GPR131, anticorps M-BAR, anticorps TGR5, anticorps Tgr5, anticorps MGC84403, anticorps GPBAR1, anticorps Gpbar1, anticorps GPCR, anticorps G protein-coupled bile acid receptor 1, anticorps G protein-coupled bile acid receptor 1 S homeolog, anticorps GPBAR1, anticorps Gpbar1, anticorps gpbar1.S

Sujet: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Alias Symbols: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5
Protein Size: 330

Poids moléculaire: 35 kDa

ID gène: 151306

NCBI Accession: NM_170699, NP_733800

UniProt: Q8TDU6

Pathways: Signalisation WNT, Hormone Transport, Sensory Perception of Sound