PDZD3 anticorps (C-Term)

N° du produit ABIN2791850

Détail du produit anti-PDZD3 anticorps

Antigène: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Porc, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZD3 est non-conjugé

Application: Western Blotting (WB)

Séquence: APLAEGWALP TKPRCLHLEK GPQGFGFLLR EEKGLDGRPG QFLWEVDPGL

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PDZD3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDZD3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDZD3

Antigène: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Autre désignation: PDZD3 (PDZD3 Produits)

Synonymes: anticorps RGD1559807, anticorps zgc:194812, anticorps IKEPP, anticorps NHERF4, anticorps PDZK2, anticorps NaPi-Cap2, anticorps Pdzk2, anticorps PDZ domain containing 3, anticorps PDZ domain containing 3b, anticorps Pdzd3, anticorps pdzd3b, anticorps PDZD3

Sujet: Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation.
Protein Interaction Partner: SPRYD7, ASAP3, SLC41A3, CACNA1S, PTGIR, SLC22A4, SLCO1A2, SLC15A2, SLCO1C1, GUCY2C, SLCO3A1, SLC22A9, SLC22A3, SLC22A5, CFTR, ABCC2, SLC15A1,
Protein Size: 571

Poids moléculaire: 62 kDa

ID gène: 79849

UniProt: Q86UT5