beta 2 Adrenergic Receptor anticorps (Middle Region)

N° du produit ABIN2792089

Détail du produit anti-beta 2 Adrenergic Receptor anticorps

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta 2 Adrenergic Receptor est non-conjugé

Application: Western Blotting (WB)

Séquence: TGEQSGYHVE QEKENKLLCE DLPGTEDFVG HQGTVPSDNI DSQGRNCSTN

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADRB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ADRB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 413 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-beta 2 Adrenergic Receptor (ABIN2792089)

Penco, Buscema, Patrosso, Marocchi, Grossi: "New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background." dans: BMC bioinformatics, Vol. 9, pp. 254, (2008) (PubMed).

Détails sur beta 2 Adrenergic Receptor

Antigène: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Autre désignation: ADRB2 (ADRB2 Produits)

Synonymes: anticorps zgc:162188, anticorps adrb2, anticorps Adrb-2, anticorps Badm, anticorps Gpcr7, anticorps ADRB2R, anticorps ADRBR, anticorps B2AR, anticorps BAR, anticorps BETA2AR, anticorps adrenoceptor beta 2, anticorps adrenoceptor beta 2, surface b, anticorps beta2-adrenergic receptor, anticorps adrenergic receptor, beta 2, anticorps ADRB2, anticorps adrb2b, anticorps LOC100136153, anticorps Adrb2

Sujet: This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Protein Interaction Partner: ARRDC3, REL, TSHR, TSG101, STAT4, STAT3, SNCG, RGS10, RGS2, RAN, RAB27A, RAB3A, CNN1, CD81, CD68, CD9, CD4, CCKBR, CEACAM1, ARRB2, ARHGDIA, ARHGAP5, HDAC6, GPR56, VAPA, RGS9, RGS11, RGS20, RGS5, VEGFB, VDAC2, VDAC1, KCTD13, ARRDC1, RGS8, SLC52A2, WNK1, RA
Protein Size: 413

Poids moléculaire: 46 kDa

ID gène: 154

NCBI Accession: NM_000024, NP_000015

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation