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RAD9A anticorps (C-Term)

RAD9A Reactivité: Humain, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792162
  • Antigène Voir toutes RAD9A Anticorps
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Épitope
    • 22
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 135
    • 49
    • 22
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Cheval
    Hôte
    • 147
    • 9
    • 1
    Lapin
    Clonalité
    • 148
    • 9
    Polyclonal
    Conjugué
    • 67
    • 15
    • 13
    • 12
    • 11
    • 11
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp RAD9A est non-conjugé
    Application
    • 137
    • 86
    • 57
    • 28
    • 27
    • 26
    • 14
    • 9
    • 8
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SLSPGPQPPK SPGPHSEEED EAEPSTVPGT PPPKKFRSLF FGSILAPVRS
    Homologie
    Horse: 84%, Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against RAD9A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human RAD9A
    Top Product
    Discover our top product RAD9A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 391 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Autre désignation
    RAD9A (RAD9A Produits)
    Synonymes
    anticorps RAD9, anticorps Rad9, anticorps rad9a, anticorps MGC89062, anticorps XRad9, anticorps rad9, anticorps RAD9 checkpoint clamp component A, anticorps RAD9 checkpoint clamp component B, anticorps RAD9 checkpoint clamp component A L homeolog, anticorps RAD9A, anticorps Rad9a, anticorps rad9a, anticorps rad9b, anticorps rad9a.L
    Sujet
    RAD9A is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM].
    Alias Symbols: RAD9
    Protein Interaction Partner: ATRX, BCL2L1, CLSPN, RAD17, MSH3, MSH2, MSH6, FEM1B, COPS5, UBC, PCNA, SF3B3, DNMT1, SETMAR, ATR, TOPBP1, HUS1B, RAD9B, ITSN2, ATAD5, DNAJC7, ATM, CHEK2, HUS1, HDAC1, AR, ABL1, BCL2, MLH1, FEN1, RPA2, RPA1, RAD1, NR3C1,
    Protein Size: 391
    Poids moléculaire
    42 kDa
    ID gène
    5883
    NCBI Accession
    NM_004584, NP_004575
    UniProt
    Q99638
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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