APBA1 anticorps (N-Term)
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- Antigène Voir toutes APBA1 Anticorps
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp APBA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- PPQQQHYVGR HQRGRALEDL RAQLGQEEEE RGECLARSAS TESGFHNHTD
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against APBA1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1
- Top Product
- Discover our top product APBA1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 837 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Autre désignation
- APBA1 (APBA1 Produits)
- Synonymes
- anticorps APBA1, anticorps 6430513E09Rik, anticorps Lin-10, anticorps Mint, anticorps Mint1, anticorps Urop11, anticorps X11, anticorps X11alpha, anticorps D9S411E, anticorps LIN10, anticorps MINT1, anticorps X11A, anticorps X11ALPHA, anticorps amyloid beta precursor protein binding family A member 1, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1b, anticorps ketopantoate reductase, anticorps 2-dehydropantoate 2-reductase, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1 (X11), anticorps amyloid beta (A4) precursor protein-binding, family A, member 1, anticorps amyloid beta (A4) precursor protein binding, family A, member 1, anticorps APBA1, anticorps apba1b, anticorps apbA1, anticorps apba1, anticorps Apba1
- Sujet
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APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Alias Symbols: D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Protein Interaction Partner: STXBP1, CNTNAP4, NRXN1, CNTNAP3, KIF17, LIN7B, KCNJ12, CCS, CACNA1B, HTR2C, CASK, NOTCH1, STX1A, APP, PSEN1, LIN7A, PSEN2, LIN7C, DLG1, APBB1,
Protein Size: 837 - Poids moléculaire
- 93 kDa
- ID gène
- 320
- NCBI Accession
- NM_001163
- UniProt
- Q02410
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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