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NF-kB p65 anticorps (N-Term)

NFkBP65 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792581
  • Antigène Voir toutes NF-kB p65 (NFkBP65) Anticorps
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    Épitope
    • 44
    • 32
    • 29
    • 28
    • 28
    • 25
    • 23
    • 23
    • 20
    • 16
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    • 15
    • 14
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    • 8
    • 5
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    N-Term
    Reactivité
    • 540
    • 373
    • 301
    • 40
    • 38
    • 28
    • 24
    • 22
    • 18
    • 17
    • 13
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Cobaye
    Hôte
    • 491
    • 53
    • 4
    • 2
    • 1
    Lapin
    Clonalité
    • 457
    • 93
    Polyclonal
    Conjugué
    • 295
    • 30
    • 23
    • 19
    • 18
    • 17
    • 17
    • 17
    • 17
    • 17
    • 16
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 2
    • 2
    • 1
    Cet anticorp NF-kB p65 est non-conjugé
    Application
    • 427
    • 203
    • 135
    • 118
    • 112
    • 104
    • 92
    • 78
    • 76
    • 29
    • 25
    • 9
    • 7
    • 7
    • 7
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    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT IKINGYTGPG
     Réactivité croisée
    Boeuf (Vache), Chien, Poulet, Humain, Souris, Porc, Rat (Rattus)
    Homologie
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against RELA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RELA
    Top Product
    Discover our top product NFkBP65 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-RELA Antibody Titration: 1.0 µg/mL
    ELISA Titer: 1:62500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 551 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    Autre désignation
    RELA / NF-kB p65 (NFkBP65 Produits)
    Synonymes
    anticorps C-Rel, anticorps NFKB3, anticorps p65, anticorps NFkB, anticorps c-rel, anticorps zgc:100833, anticorps Xrel2, anticorps Xrel3, anticorps rel, anticorps rel-A, anticorps rel2, anticorps rel3, anticorps v-rel, anticorps xrel, anticorps REL proto-oncogene, NF-kB subunit, anticorps RELA proto-oncogene, NF-kB subunit, anticorps v-rel reticuloendotheliosis viral oncogene homolog A (avian), anticorps v-rel avian reticuloendotheliosis viral oncogene homolog, anticorps v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog, anticorps REL, anticorps RELA, anticorps Rela, anticorps Rel, anticorps rel, anticorps rel.L
    Sujet
    P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
    Alias Symbols: p65, NFKB3
    Protein Interaction Partner: GAN, CCND1, ABCA1, UBC, TCF4, SRSF7, RELA, REL, PRKDC, PLG, PEX1, NFKB2, NFKB1, MUC3A, KRT5, REV1, TXN2, FBXW11, IL1RN, IKBKB, HSPA5, HDAC1, EP300, CREBBP, MAP3K8, CHEK1, CDKN2A, CDK4, SPATA31A3, POTEJ, POTEE, PIWIL4, DIS3L2, DCD, IKBKG, CHUK, PLA2G4A, ST
    Protein Size: 551
    Poids moléculaire
    60 kDa
    ID gène
    5970
    NCBI Accession
    NM_021975, NP_068810
    UniProt
    Q04206
    Pathways
    Signalisation NF-kappaB, Signalisation RTK, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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