anti-Histone H1 anticorps

Aperçu

Antigène:	Histone H1
Clonalité:	Monoclonal (AE-4)
Application:	Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Reactivité:	Human
Hôte:	Mouse
Quantité:	200 µg (1 mg/ml)
Prix:	460,00 $ (Plus frais de livraison $25 et TVA, Invoice in EUR)
Numéro du produit:	ABIN291574
Disponibilité:	Envoi sous 10 à 15 jours ouvrables

Antigène	Histone H1
Immunogène	Nuclei from myeloid leukemia biopsy cells
Reactivité	Human
Clonalité	Monoclonal
Isotype	IgG2a »Anticorps secondaires correspondants
Description	Gene: Histone H1.
Clone	AE-4
Hôte	Mouse
Specificité	Recognizes histone H1. The histone proteins serve as a structural scaffold for the organization of nuclear DNA into chromatin. In eukaryotic cells there are 4 core histone proteins, H2A, H2B, H3 and H4 that assemble to form an octamer round which the DNA is wrapped in a sequence dependant manner. The resulting complex is known as a nucleosome and is the basic subunit of chromatin. Histone H1 acts as a linker and binds to each nucleosome, and by self affinity, links these nucleosomes together resulting in the 30 nm chromatin fiber. In blots of rat brain homogenate a duplet is observed at 27-29 kD consistent with Histone H1. Speckled staining is observed in the nucleus of normal and malignant cells.

Application	Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Indications d'application	WB (1:100), ELISA, IF, IHC-P, IHC-Fr
Concentration	1 mg/ml
Purification	Protein G Column
Buffer	PBS, 0.09% sodium azide.
Stock	Long term: -20°C, Short term: -20°C
Restrictions	For Research Use only