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TUBA1B anticorps (Biotin)

TUBA1B Reactivité: Porc WB Hôte: Souris Monoclonal TU-01 Biotin
N° du produit ABIN303511
  • Antigène Voir toutes TUBA1B Anticorps
    TUBA1B (Tubulin, alpha 1B (TUBA1B))
    Reactivité
    • 45
    • 25
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Porc
    Hôte
    • 36
    • 11
    • 1
    Souris
    Clonalité
    • 34
    • 14
    Monoclonal
    Conjugué
    • 26
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TUBA1B est conjugé à/à la Biotin
    Application
    • 43
    • 20
    • 17
    • 14
    • 13
    • 10
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    The antibody TU-01 recognizes the defined epitope (aa 65-97) on N-terminal structural domain of alpha-tubulin.
    Immunogène
    Fraction of tubulin purified from porcine brain by two cycles of polymerization - depolymerization.
    Clone
    TU-01
    Isotype
    IgG1
    Top Product
    Discover our top product TUBA1B Anticorps primaire
  • Indications d'application
    Western Blotting (1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH ~7.4, 15 mM Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Antigène
    TUBA1B (Tubulin, alpha 1B (TUBA1B))
    Autre désignation
    alpha Tubulin / TUBA1B (TUBA1B Produits)
    Synonymes
    anticorps RGD1565476, anticorps K-ALPHA-1, anticorps cb944, anticorps fb22g06, anticorps tuba1, anticorps wu:fb22g06, anticorps Tuba2, anticorps TUBA3, anticorps k-alpha-1, anticorps tuba, anticorps Calpha1, anticorps Tuba1, anticorps TUBA1B, anticorps tubulin, alpha 1B, anticorps tubulin alpha 1b, anticorps tubulin, alpha 1b, anticorps tubulin alpha 1b L homeolog, anticorps tubulin alpha-1B chain, anticorps Tubulin alpha-1B chain, anticorps Tuba1b, anticorps TUBA1B, anticorps tuba1b, anticorps tuba1b.L, anticorps LOC100445003, anticorps LOC102178700
    Sujet
    The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). The microtubules consist of 13 protofilaments and have an outer diameter 25 nm. Microtubules have their intrinsic polarity, highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. On a practical level, microtubules can easily be stabilized by the addition of non-hydrolysable analogues of GTP (eg. GMPPCP) or more commonly by anti-cancer drugs such as Taxol. Taxol stabilizes microtubules at room temperature for many hours. Using limited proteolysis by enzymes both tubulin subunits can be divided into N-terminal and C-terminal structural domains. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain
    ID gène
    10376
    NCBI Accession
    NP_006073
    UniProt
    P68363
    Pathways
    Dynamique des Microtubules, M Phase
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