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SMAD5 anticorps (Middle Region)

SMAD5 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043980
  • Antigène Voir toutes SMAD5 Anticorps
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    Épitope
    • 27
    • 27
    • 15
    • 13
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 248-267, Middle Region
    Reactivité
    • 97
    • 61
    • 48
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Rat
    Hôte
    • 86
    • 11
    Lapin
    Clonalité
    • 72
    • 25
    Polyclonal
    Conjugué
    • 41
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp SMAD5 est non-conjugé
    Application
    • 83
    • 38
    • 29
    • 26
    • 15
    • 10
    • 10
    • 9
    • 9
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 5(SMAD5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    IPQIMPSISS RDVQPVAYEE
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 5(SMAD5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: SMAD family member 5
    Protein Name: Mothers against decapentaplegic homolog 5
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence in the middle region of human SMAD5(248-267aa IPQIMPSISSRDVQPVAYEE), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product SMAD5 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for SMAD5 is approximately 1.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    Autre désignation
    SMAD5 (SMAD5 Produits)
    Synonymes
    anticorps DWFC, anticorps JV5-1, anticorps MADH5, anticorps Madh5, anticorps SBN, anticorps fb67b04, anticorps mad, anticorps madh5, anticorps sb:cb400, anticorps smd5, anticorps wu:fb67b04, anticorps SMAD5, anticorps DKFZp468M0619, anticorps 1110051M15Rik, anticorps AI451355, anticorps Dwf-C, anticorps MusMLP, anticorps SMAD family member 5, anticorps SMAD5, anticorps Smad5, anticorps smad5
    Sujet
    Mother against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SAMD5 gene. It belongs to the SMAD family of proteins, which belong to the TGFbeta superfamily of modulators. The gene was assigned to human chromosome 5q31. Like many other TGFbeta family members SMAD5 is involved in cell signalling and modulates signals of bone morphogenetic proteins(BMP's). It may play a role in the pathway where TGFbeta is an inhibitor of hematopoietic progenitor cells.

    Synonyms: DKFZp781C1895 antibody|DKFZp781O1323 antibody|Dwfc antibody|hSmad 5 antibody|hSmad5 antibody|JV5 1 antibody|JV5-1 antibody|MAD homolog 5 antibody|MAD mothers against decapentaplegic homolog 5 antibody|MAD, mothers against decapentaplegic homolog 5 antibody|MADH 5 antibody|MADH5 antibody|Mothers against decapentaplegic homolog 5 antibody|Mothers against DPP homolog 5 antibody|MusMLP antibody|SMA and MAD related protein 5 antibody|SMAD 5 antibody|SMAD family member 5 antibody|SMAD mothers against DPP homolog 5 antibody|Smad5 antibody|SMAD5_HUMAN antibody
    UniProt
    Q99717
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