TRPC6 anticorps (Middle Region)

N° du produit ABIN3044146

Détail du produit anti-TRPC6 anticorps

Antigène: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Épitope: AA 249-265, Middle Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 6(TRPC6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: HDYFCKCNDC NQKQKHD

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 6(TRPC6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: transient receptor potential cation channel, subfamily C, member 6
Protein Name: Short transient receptor potential channel 6(TrpC6)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TRPC6(249-265aa HDYFCKCNDCNQKQKHD), different from the related rat and mouse sequences by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-TRPC6 (ABIN3044146)

Wang, Wang, Li: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." dans: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).

Détails sur TRPC6

Antigène: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Autre désignation: TRPC6 (TRPC6 Produits)

Synonymes: anticorps FSGS2, anticorps TRP6, anticorps AV025995, anticorps LLHWJM002, anticorps LLHWJM003, anticorps LLHWJM004, anticorps TRP-6, anticorps Trrp6, anticorps mtrp6, anticorps trp6, anticorps bZ1P14.9, anticorps si:rp71-1p14.9, anticorps trpc6, anticorps transient receptor potential cation channel subfamily C member 6, anticorps transient receptor potential cation channel, subfamily C, member 6, anticorps transient receptor potential cation channel, subfamily C, member 6a, anticorps TRPC6, anticorps Trpc6, anticorps trpc6a, anticorps trpc6

Sujet: Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Synonyms: bZ1P14.9 antibody|FLJ11098 antibody|FLJ14863 antibody|FSGS2 antibody|MTRP6 antibody|Short transient receptor potential channel 6 antibody|si:rp71-1p14.9 antibody|Transient Receptor Potential Cation Channel Subfamily C Member 6 antibody|Transient receptor protein 6 antibody|TRP 6 antibody|TRP-6 antibody|TRP6 antibody|TRPC 6 antibody|TrpC6 antibody|Trpc6 antibody|TRPC6_HUMAN antibody|TRRP6 antibody

UniProt: Q9Y210