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ETV5 anticorps (N-Term)

ETV5 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN309622
  • Antigène Voir toutes ETV5 Anticorps
    ETV5 (Ets Variant 5 (ETV5))
    Épitope
    • 16
    • 15
    • 12
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 66
    • 29
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 54
    • 12
    Lapin
    Clonalité
    • 55
    • 11
    Polyclonal
    Conjugué
    • 24
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ETV5 est non-conjugé
    Application
    • 56
    • 34
    • 14
    • 13
    • 13
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MDGFYDQQVP FMVPGKSRSE ECRGRPVIDR KRKFLDTDLA HDSEELFQDL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
    Attributs du produit
    This is a rabbit polyclonal antibody against ETV5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human ETV5
    Top Product
    Discover our top product ETV5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 510 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ETV5 (Ets Variant 5 (ETV5))
    Autre désignation
    ETV5 (ETV5 Produits)
    Synonymes
    anticorps ERM, anticorps etv5, anticorps fj87h10, anticorps id:ibd5133, anticorps wu:fj87h10, anticorps zgc:55647, anticorps 1110005E01Rik, anticorps 8430401F14Rik, anticorps ETS variant 5, anticorps ets variant 5, anticorps ets variant 5a, anticorps ETV5, anticorps Etv5, anticorps etv5a
    Sujet
    ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer.
    Alias Symbols: ERM
    Protein Interaction Partner: RFWD2, HDAC11, DHRS7, SEZ6L2, SLC22A2, HOXD9, CYP3A5, CCR5, CISH, AMH, APP, BRCA1, ELAVL1, SUMO2, UBC, AR,
    Protein Size: 510
    Poids moléculaire
    58 kDa
    ID gène
    2119
    NCBI Accession
    NM_004454, NP_004445
    UniProt
    P41161
    Pathways
    Synaptic Membrane, Skeletal Muscle Fiber Development
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