TLE2 anticorps (N-Term)

N° du produit ABIN309653

Détail du produit anti-TLE2 anticorps

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE2 est non-conjugé

Application: Western Blotting (WB)

Séquence: VEEERPSGPG GGGKQRADEK EPSGPYESDE DKSDYNLVVD EDQPSEPPSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TLE2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 743 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TLE2

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Autre désignation: TLE2 (TLE2 Produits)

Synonymes: anticorps TLE2, anticorps ESG, anticorps ESG2, anticorps GRG2, anticorps Grg2, anticorps mKIAA4188, anticorps transducin like enhancer of split 2, anticorps transducin-like enhancer of split 2, anticorps TLE2, anticorps Tle2

Sujet: TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: ESG, ESG2, FLJ41188, GRG2
Protein Interaction Partner: UBC, SUMO1, ORF50, LEF1, BARHL1, TLX3, VENTX, CUL4A, CUL4B, PAX9, MSX2, MSX1, FOXA3, EMX2, PRDM1, H3F3B, TLE1, UTY, HMGB1, RUNX1, TLE2, HES1,
Protein Size: 743

Poids moléculaire: 80 kDa

ID gène: 7089

NCBI Accession: NM_003260, NP_003251

UniProt: Q04725

Pathways: Signalisation WNT