TAF6 anticorps (N-Term)

N° du produit ABIN309749

Détail du produit anti-TAF6 anticorps

Antigène: TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LTDEVSYRIK EIAQDALKFM HMGKRQKLTT SDIDYALKLK NVEPLYGFHA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TAF6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 667 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TAF6 (ABIN309749)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur TAF6

Antigène: TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

Autre désignation: TAF6 (TAF6 Produits)

Synonymes: anticorps CG32211, anticorps CG9348, anticorps Dmel\\CG32211, anticorps SR3-4B, anticorps TAF, anticorps TAF6, anticorps TAF60, anticorps TAF60/62, anticorps TAFII60, anticorps TAFII60(62), anticorps TAFII62, anticorps TAF[[II]], anticorps TAF[[II]]60, anticorps TAF[[II]]60/62, anticorps TAF[[II]]62, anticorps TFIID, anticorps TFIID 62, anticorps Taf-6, anticorps Taf60, anticorps Taf62, anticorps Taf[[II]]60, anticorps d60, anticorps dTAF6, anticorps dTAF62, anticorps dTAFII62, anticorps dTAF[[II]]262, anticorps dTAF[[II]]60, anticorps dTAF[[II]]62, anticorps dmTAF6, anticorps dme-TAFII60, anticorps l(3)76BDf, anticorps p62, anticorps taf6, anticorps taf60, anticorps wu:fb83e08, anticorps wu:fj30b02, anticorps zgc:92160, anticorps 80kDa, anticorps AW549759, anticorps TAF(II)80, anticorps TAFII70, anticorps Taf2e, anticorps p80, anticorps TAF(II)60, anticorps MGC:8964, anticorps TAF(II)70, anticorps TAF2E, anticorps TAFII-70, anticorps TAFII-80, anticorps TAFII80, anticorps TAFII85, anticorps TBP-associated factor 6, anticorps TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, anticorps TATA-box binding protein associated factor 6, anticorps TATA-box binding protein associated factor 6 L homeolog, anticorps Taf6, anticorps taf6, anticorps taf6.L, anticorps TAF6

Sujet: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
Alias Symbols: DKFZp781E21155, MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85, TAFII-70, TAFII-80, TAF(II)70, TAF(II)80
Protein Interaction Partner: SOX5, HNF4A, MED26, TRRAP, HIST3H3, UBC, TBP, AHR, APP, TAF1L, TAF3, TAF9B, TAF10, TAF9, TAF7, TAF5, TAF4, TAF2, TAF1, KMT2A, USF1, ERCC1, TAF8, KAT2A, SETD7, NR1D2, NCOR1, NFYC, NFYB, NFYA, MBD3, SIN3A, ALL1, SAP30, SMARCC2, SMARCC1, SMARCB1, SMARCA2, RB
Protein Size: 667

Poids moléculaire: 71 kDa

ID gène: 6878

NCBI Accession: NM_139122, NP_620834

UniProt: A4D2B3