L3MBTL2 anticorps (C-Term)

N° du produit ABIN309963

Détail du produit anti-L3MBTL2 anticorps

Antigène: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Épitope: C-Term

Reactivité: Humain, Chien, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L3MBTL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLEDDPQGAR KISSEPVPGE IIAVRVKEEH LDVASPDKAS SPELPVSVEN

Homologie: Cow: 85%, Dog: 85%, Horse: 85%, Human: 100%, Pig: 92%

Attributs du produit: This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 705 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-L3MBTL2 (ABIN309963)

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." dans: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Détails sur L3MBTL2

Antigène: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Autre désignation: L3MBTL2 (L3MBTL2 Produits)

Synonymes: anticorps L3MBTL2, anticorps im:7137244, anticorps wu:fb04e09, anticorps zgc:66491, anticorps H-l(3)mbt-l, anticorps L3MBT, anticorps 4732493N06Rik, anticorps M4mbt, anticorps L3MBTL2 polycomb repressive complex 1 subunit, anticorps L3MBTL2, polycomb repressive complex 1 subunit, anticorps l(3)mbt-like 2 (Drosophila), anticorps L3MBTL2, anticorps l3mbtl2, anticorps L3mbtl2

Sujet: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
Alias Symbols: H-l(3)mbt-l, L3MBT
Protein Interaction Partner: TRIM42, STAC3, PHF10, TBC1D9B, PAICS, AES, SUMO2, SUMO1, PIAS1, HIST1H4A, HIST1H3A, RNF2, MPP3, PCGF6, RYBP, YAF2, SMARCAD1, HIST4H4, CBX3, HIST3H3, E2F6, Lin54, HDAC3, MEAF6, STAM2, RB1,
Protein Size: 705

Poids moléculaire: 79 kDa

ID gène: 83746

NCBI Accession: NM_031488, NP_113676

UniProt: Q969R5