RPN1 anticorps (N-Term)

N° du produit ABIN310034

Détail du produit anti-RPN1 anticorps

Antigène: RPN1 (Ribophorin 1 (RPN1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TSRATSFLLA LEPELEARLA HLGVQVKGED EEENNLEVRE TKIKGKSGRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 100%, Zebrafish: 80%

Attributs du produit: This is a rabbit polyclonal antibody against RPN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RPN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 607 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RPN1 (ABIN310034)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur RPN1

Antigène: RPN1 (Ribophorin 1 (RPN1))

Autre désignation: RPN1 (RPN1 Produits)

Synonymes: anticorps OST1, anticorps RBPH1, anticorps AU018702, anticorps D6Wsu137e, anticorps Rpn-1, anticorps RIBI, anticorps wu:fa12h07, anticorps wu:fc68b07, anticorps wu:fc88a12, anticorps ost1, anticorps xrpn1, anticorps ribophorin I, anticorps ribophorin I L homeolog, anticorps PVX_119685, anticorps NAEGRDRAFT_78171, anticorps RPN1, anticorps Rpn1, anticorps rpn1, anticorps rpn1.L

Sujet: RPN1 is a type I integral membrane protein found only in the rough endoplasmic reticulum. It is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. RPN1 forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686B16177, OST1, RBPH1
Protein Interaction Partner: UBQLN1, UBC, SGTA, SUMO3, STAU1, LGR4, SUMO1, NEDD8, MDM2, ASB5, ASB11, BMI1, EED, RNF2, EGFR, ADRB2, CLN5, CLN3, AMFR, OST4, MMS19, env, UBL4A, WHSC1, VCAM1, FN1, ATF2, VCP, ESR1, ECT2, STT3B, SND1, SYNCRIP, TECR, VDAC2, SSR3, RPN2, RPSA, ILF3, SLC25A5,
Protein Size: 607

Poids moléculaire: 69 kDa

ID gène: 6184

NCBI Accession: NM_002950, NP_002941

UniProt: P04843