LCAT anticorps (N-Term)

N° du produit ABIN310203

Détail du produit anti-LCAT anticorps

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Mouton, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCAT est non-conjugé

Application: Western Blotting (WB)

Séquence: MGPPGSPWQW VTLLLGLLLP PAAPFWLLNV LFPPHTTPKA ELSNHTRPVI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LCAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LCAT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 440 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LCAT (ABIN310203)

Hirata, Yimin, Segawa, Ozaki, Kobayashi, Shigyo, Chiba: "Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice." dans: PLoS ONE, Vol. 7, Issue 11, pp. e49415, (2012) (PubMed).

Détails sur LCAT

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Autre désignation: LCAT (LCAT Produits)

Synonymes: anticorps AI046659, anticorps D8Wsu61e, anticorps MGC82035, anticorps lcat, anticorps MGC88964, anticorps LCAT, anticorps lecithin-cholesterol acyltransferase, anticorps lecithin cholesterol acyltransferase, anticorps lecithin-cholesterol acyltransferase L homeolog, anticorps solute carrier family 12 member 4, anticorps fragile site, aphidicolin type, common, fra(13)(q13.2), anticorps LCAT, anticorps Lcat, anticorps lcat.L, anticorps lcat, anticorps SLC12A4, anticorps FRA13A

Sujet: LCAT is an extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in its gene have been found to cause fish-eye disease as well as LCAT deficiency.This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Protein Interaction Partner: APOA1, EXOSC10, APOE, APOA2, A2M,
Protein Size: 440

Poids moléculaire: 48 kDa

ID gène: 3931

NCBI Accession: NM_000229, NP_000220

UniProt: P04180

Pathways: Lipid Metabolism